“In my trips, I’ve seen that death is beautiful. “I ‘died’ during my first trip,” Tyson said. Making news headlines over the last month was heavyweight fighter Mike Tyson’s endorsement of the substance as a positive catalyst that transformed his life. Shorter duration psychedelic treatments will likely scale better than other psychedelic treatments, such as therapies using psilocybin or MDMA, which can require five to eight hours from clinicians involved in administering and monitoring patients.īiopharmaceutical companies are keenly aware of creating therapies that require less time and fewer clinician hours in the hopes of health insurance providers covering treatments, as is the case with ketamine treatments.Īnother key action of 5-MeO-DMT is its ability to produce ego loss or “ego death” during an experience using the drug, which can produce valuable insights that change one’s overall perception of life and its difficulties.
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So far, GH Research is on track to validate claims that their proprietary GH001 5-MeO-DMT formula is safe and could provide relief from TRD with no serious adverse events for patients.Ĭompleting two Phase 1 healthy-volunteer clinical trials and a Phase 1/2 clinical trial in patients with TRD, studies have so far revealed that 87.5% of patients were brought into an ultra-rapid remission after an individualized single-day dosing regimen using GH Research’s inhalable 5-MeO-DMT product.įast action the key: Part of what makes the substance valuable for clinicians treating depression is the drug’s potency and fast-acting nature, with onset occurring within seconds and treatments lasting on average a relatively rapid 15 to 20 minutes.
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The lack of effective treatments for TRD has created a market for companies like GH Research seeking to develop such therapies, potentially changing the way TRD is treated today. Currently, an estimated 50 percent of patients receiving therapy for TRD do not respond to approved depression medications. The Ireland-based company, which this year announced a capital raise of $315 million, is focused exclusively on research around the psychoactive molecule 5-MeO-DMT to treat depression, a condition that affects many millions of people around the world. Once the download completes, the installation will start and you'll get a notification after the installation is finished.Clinical-stage biopharmaceutical company GH Research PLC (NASDAQ: GHRS) announced positive results from recent clinical trials of its leading 5-MeO-DMT formula, a therapy candidate for patients suffering from treatment-resistant depression (TRD).
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